Correct Answer - D
Ans. D. Lichen planus
LP is characterized by shiny, violaceous, flat-topped polygonal
papules which retain the skin lines.
White lines, known as Wickham's striae, may traverse the surface of
the papules.
Linear lesions often appear along scratch marks or in scars
(Koebner phenomenon).
In most cases, the papules eventually flatten after a 6 months to 2 yrs, often to be replaced by an area of hyperpigmentation.
@dermatology_vid
Correct Answer - B
Ans. B. Reverse Koebner's phenomenon
Annular orange skin lesions in a diabetic indicate towards granuloma annulare.
There have been few reports of disappearance of lesions after
biopsy in granuloma annulare.
This phenomenon is known as reverse Koebner's phenomenon.
@dermatology_vid
Correct Answer - D
Ans. D. DNA repair defect
[Ref Rook's 4thie p. 78.12]
Xeroderma pigmentosa
Molecular defect:
Exposure to UV rays damages DNA due to production of convalent
linkages between adjacent pyrimidines (pyrimidine dimmers).
Normally the damaged DNA is repaired by excision and repair.
In xeroderma pigmentosa the repair of UV damaged DNA is
defective.
It is an autosomal recessive disorder.
@dermatology_vid
Correct Answer - B
Ans. is 'b' i.e., Bechet's syndrome
Criteria for diagnosis of Bechet's disease
Recurrent oral ulcer for at least 3 times in 12 months.
Plus any two of the followings :?
1. Recurrent genital ulcer.
2. Eye inflammation with loss of vision.
3. Characterstic skin lesion (erythema nodosum).
4. Positive pathergy test (skin prick test)
@dermatology_vid
Correct Answer - A
Answer- A. Palpable purpura
Palpable purpura is essential for diagnosis.
Diagnosis is confirmed by presence of palpable purpura with normal
platelet count along with one or more of the following : abdominal
pain, arthralgia/arthritisand mesangial deposition of IgA.
@dermatology_vid
Correct Answer - A
Ans. A. Idiopathic
[Ref: Neena Khanna Yale p. 61, 63]
Erythema multiforme
Most of the cases of erythema multiforme are idiopathic, but
amongst the causative agents Herpes simplex virus is the most
important cause.
Erythema multiforme is an acute, often self limited erutption
characterized by a distinctive clinical eruption, the hallmark of which is the Target lesion (Iris lesion or Bulle's eye lesion).
@dermatology_vid
Correct Answer - C
Pemphigus vulgaris is an intraepidermal blistering disease.
@dermatology_vid
Correct Answer - C
Ans. is 'c' i.e., Clubbing
Clinical indicators of clubbing are
Lovibond profile sign and
curth's modified profile sign".
Lovibond angle is the angle located at the junction between the nail
plate and proximal nail fold. It is normally less than 160°.
In clubbing, the angle exceeds 180° (Lovibond profile sign).
@dermatology_vid
Correct Answer - A
Ans. is 'a' i.e., Hydroquinone
Skin depigmenting agents in clinical use are
Hydroquinone - most effective and widely used
Kojic acid
Kojicdipalmitate
Azelaic acid
@dermatology_vid
Correct Answer - A
Ans. A. Penicillamine
Drugs causing pemphigus
Penicillamine
Penicillins and Cefalosporins
Captopril,
Iodine,
Lithium
Phenophthelin,
Propanolol
Rifampicine
Phenytoin,
Phenylbutazone,
Salicylates,
Piroxicam,
Sulphonamides
@dermatology_vid
Correct Answer - C
Ans. C. Post inflammatory hypomelanosis
[Ref IADVL 3"1/e p. 747-748]
Among given options, postinflammatory hypomelanosis is the best answer.
understand let us have a look at the definition few important terms.
Vitiligo is also an acquired condition with loss of pigmentation but most cases are idiopathic.
It is mainly considered to be an autoimmune condition.
Precipitated by hormonal changes, acute emotional trauma or stress
or any condition leading to immune imbalance.
So, any hypomelanosis resulting after inflammation is known as post inflammatory hypomelanosis (including leucoderma).
Sometimes both the terms are used synonymously.
Whereas the term 'chemical leucoderma' is used only when there repeated exposure (contact) to some specific chemical.
Therefore among given options, postinflammatory hypomelanosis is the best answer as drug reaction is an inflammatory condition
leading to residual hypopigmentatio
@dermatology_vid
Correct Answer - B
Ans. B. Acanthosis
[Ref Rook's 7th/e p. 7.36]
Important terminology related to epidermal layers Separation of keratinocytes due to loss of intracellular bridges - Acantholysis
Intracellular edema of keratinocytes Ballooning
@dermatology_vid
Correct Answer - A
Ans.A. Keratinocyte
Tzank cells are acanthoylytic cells i.e. large rounded keratinocytes
with relatively large nucleus with condensed or hazy cytoplasm.
@dermatology_vid
Correct Answer - B
Ans. B. Polyhedral
5 characteristic 'P’ of lichen planus
1. Pruritic (itching)
2. Polygonal
3. Purple (violaceous)
4. Plane (flat topped)
5. Papule or plaque
These 5 Ps are the characteristic features of lichen planus lesions
presentation.
@dermatology_vid
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Correct Answer - A
Ans. A. Remain constant throughout life time of a person
[Ref: IADVL text book of dermatology 3rd le p. 175 & Internet]
Langer's lines
Also called cleavage lines, is a term used to define the direction
within the human skin along which the skin has the least flexibility.
These lines correspond to the alignment of collagen fibers within the dermis.
Usually, a surgical cut is carried out in the direction of langer's lines,
and incisions made parallel to langer's lines generally heal better
and produce less scarring.
Directional changes of Langer's lines have been known to occur
within the course of a person's lifetime.
Sometimes the exact direction of these lines are unknown, because
in some regions of the body there are differences between different
individuals
@dermatology_vid
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Correct Answer - A
Ans. is 'a' i.e., N. gonococci
Information in this question are ?
1. Gram negative diplococci.
2. Growth on modified Thayer-martin media.
o Neisseria gonorrhoeae is a gram negative diplococci and Thayermartin medium is the selective medium for gonococci.
Lab diagnosis of gonorrhea
Urethral discharge is the most important specimen.
Transport media
1. La It processing is to occur within 6 hrs ---> Stuart medium or A mies medium.
2. If processing is to occur > 6 hrs —> JEMBEC or Gono - Pak
system (media with self - contained CO2 -generating system).
Cluture media
1. In acute cases --> Chocolate agar or Muller - Hinton agar.
2. In chronic cases ---> Selective medium - Thayer martin medium.
Normally the diagnosis of gonorrhoea is made by isolating the organism in culture
@dermatology_vid
Correct Answer - D
Ans. D. DNA repair defect
[Ref Rook's 4thie p. 78.12]
Xeroderma pigmentosa
Molecular defect:
Exposure to UV rays damages DNA due to production of convalent
linkages between adjacent pyrimidines (pyrimidine dimmers).
Normally the damaged DNA is repaired by excision and repair.
In xeroderma pigmentosa the repair of UV damaged DNA is defective.
It is an autosomal recessive disorder
@dermatology_vid
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Correct Answer - B
Ans. B. Reverse Koebner's phenomenon
[Refhttps://www.researchgate.net/publication/268343496_Proposed_
classification_for_koebner_wolf
isotopic_renbok_koebner_nonreaction_isotopic_nonreaction_other_relatedphenomen]
Annular orange skin lesions in a diabetic indicate towards granuloma annulare.
There have been few reports of disappearance of lesions after
biopsy in granuloma annulare.
This phenomenon is known as reverse Koebner's phenomenon.
@dermatology_vid
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Ans. A.Cold temperature
Cutis marmorata is a condition where in the skin has a pinkish blue mottled or marbled appearance when subjected to cold temperatures.
It is seen throughout infancy and in 50 % of children.
Rewarming restores the skin to normal.
It is caused by superficial small blood vessels in the skin dilating and contracting at the same time .
@dermatology_vid
Correct Answer - C
Ans. C. Popliteal fossa
Sites of itching patch in atopic dermatitis Infant; Face (especially cheek), extensors offorearm& legs.
Childhood & adult > Flexures (antecubitalrbitalfoxa,Poplitealfossa).
@dermatology_vid
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Correct Answer - B
Ans. B. Stratum granulosum
Odland bodies are membrane coated granules in stratum
granulosum, which contain lipids which is responsible for barrier
function of this layer.
This layer also contains diamond shaped keratohyaline granules,
which are the characteristic features of this layer.
These keratohyaline granules contain filaggrin protein which is
responsible for aggregation of keratin filaments.
@dermatology_vid
