New CRISPR breakthrough promises more affordable disease diagnostics
A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise, and more affordable, while opening the door to entirely new ways of controlling disease.
news-medical.net/news/20260515/New-CRISPR-breakthrough-promises-more-affordable-disease-diagnostics.aspx
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Study improves prediction of dangerous outcomed from hypertrophic cardiomyopathy
A sweeping international study has identified ways to detect patients who are at serious risk of sudden death, heart failure or other dangerous outcomes from heart thickening known as hypertrophic cardiomyopathy.
news-medical.net/news/20260513/Study-improves-prediction-of-dangerous-outcomed-from-hypertrophic-cardiomyopathy.aspx
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Implantable cytokine factories show promise against advanced ovarian cancer
Implantable cytokine factories designed to deliver immunotherapy directly at the site of disease have taken an important step toward clinical reality.
news-medical.net/news/20260512/Implantable-cytokine-factories-show-promise-against-advanced-ovarian-cancer.aspx
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Scientists call for explainable AI in protein language models
Protein language models are artificial intelligence tools which help engineer proteins with useful properties, including completely new structures never seen before in nature.
news-medical.net/news/20260511/Scientists-call-for-explainable-AI-in-protein-language-models.aspx
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Nuclera launches antibody triage service to advance AI-driven antibody discovery
Nuclera, the biotechnology company enabling rapid access to high-quality proteins, today announced the launch of its antibody screening service to streamline the transition from antibody hit generation to lead selection.
news-medical.net/news/20260511/Nuclera-launches-antibody-triage-service-to-advance-AI-driven-antibody-discovery.aspx
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Nuclera launches antibody triage service to advance AI-driven antibody discovery
Nuclera, the biotechnology company enabling rapid access to high-quality proteins, today announced the launch of its antibody screening service to streamline the transition from antibody hit generation to lead selection.
news-medical.net/news/20260511/Nuclera-launches-antibody-triage-service-to-advance-AI-driven-antibody-discovery.aspx
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New ‘heart-on-a-chip’ to halt cardiac damage caused by Duchenne
Duchenne Parent Project Spain (DPPE) has launched the BEAT Project, a research initiative focused on one of the key challenges associated with Duchenne and Becker muscular dystrophies: progressive heart damage. Cardiomyopathy is the leading cause of death in patients with DMD.
news-medical.net/news/20260507/New-e28098heart-on-a-chipe28099-to-halt-cardiac-damage-caused-by-Duchenne.aspx
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New blood test predicts illness progression and treatment response
Scientists are developing a test which could one day be used to predict how a patient's illness will progress, and even how well they will respond to treatment.
news-medical.net/news/20260506/New-blood-test-predicts-illness-progression-and-treatment-response.aspx
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Genetic background shapes outcomes in chromosome 16 deletion disorders
Individuals that share the same deletion of a portion of chromosome 16 are at risk of developing neurodevelopmental disorders, but some experience severe intellectual disability or developmental delay, while others may only exhibit milder psychiatric features like depression or anxiety.
news-medical.net/news/20260505/Genetic-background-shapes-outcomes-in-chromosome-16-deletion-disorders.aspx
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New tools for quicker and easier Mpox diagnosis
Following the rise in monkeypox (Mpox) cases, particularly in countries where the disease had not traditionally been observed, the World Health Organization (WHO) declared a Public Health Emergency of International Concern in June 2022 and again in August 2024.
news-medical.net/news/20260504/New-tools-for-quicker-and-easier-Mpox-diagnosis.aspx
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Portable MiniDock MTB delivers tuberculosis results in thirty minutes
Drugs to treat tuberculosis have been around for more than 75 years, yet it remains the world's top infectious disease killer.
news-medical.net/news/20260430/Portable-MiniDock-MTB-delivers-tuberculosis-results-in-thirty-minutes.aspx
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New AI models quickly find compounds that target Lyme bacteria
Tufts University researchers are using AI and machine learning to more quickly identify potential narrow-spectrum antibiotics to prevent and treat Lyme disease, thanks to a generous gift from an alumnus that sped up their timeline by two to three years.
news-medical.net/news/20260428/New-AI-models-quickly-find-compounds-that-target-Lyme-bacteria.aspx
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AI tools can predict ADHD risk years before a formal diagnosis
Attention-deficit/hyperactivity disorder (ADHD) affects millions of children, yet many go years without a diagnosis, missing the chance for early support that can change long-term outcomes even when early signs are present.
news-medical.net/news/20260427/AI-tools-can-predict-ADHD-risk-years-before-a-formal-diagnosis.aspx
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Air quality in infancy may fundamentally shape long-term immune development
Ambient air pollution is associated with respiratory infection burden in the first year of life, according to preliminary findings from the Immune Development in Early Life (IDEaL) Rome Cohort. Findings from the cohort will be presented during the Pediatric Academic Societies (PAS) 2026 Meeting, taking place April 24-27 in Boston.
news-medical.net/news/20260424/Air-quality-in-infancy-may-fundamentally-shape-long-term-immune-development.aspx
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Qureight to support Mediar Therapeutics' Phase 2 trial of MTX-474 in diffuse cutaneous Systemic Sclerosis
Qureight, an end-to-end imaging CRO that provides enterprise-grade imaging and precision endpoints for clinical trials with a focus on lung and heart disease, and Mediar Therapeutics (Mediar), a clinical-stage biotechnology company advancing first-in-class therapies designed to halt fibrosis, today announced Qureight's AI-powered 3D quantitative imaging analytics platform and services will be used to support Mediar's Phase 2 EncompaSSc clinical trial.
news-medical.net/news/20260513/Qureight-to-support-Mediar-Therapeutics-Phase-2-trial-of-MTX-474-in-diffuse-cutaneous-Systemic-Sclerosis.aspx
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New mRNA adjuvant dramatically boosts T-cell vaccine responses in mice
MIT engineers have developed a new way to amplify the T-cell response to mRNA vaccines - an advance that could lead to much more powerful cancer vaccines and stronger protection against infectious diseases.
news-medical.net/news/20260513/New-mRNA-adjuvant-dramatically-boosts-T-cell-vaccine-responses-in-mice.aspx
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Using AI to improve success rates of fecal microbiota transplants
MOZAIC leverages deep learning to optimize fecal microbiota transplantation, enhancing treatment efficacy through precise donor-recipient microbiome matching.
news-medical.net/news/20260512/Using-AI-to-improve-success-rates-of-fecal-microbiota-transplants.aspx
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Uncountable expands specialty chemicals footprint with four new deals
Uncountable, a software company that develops AI platforms for end-to-end product development, today announced it has signed four new agreements with specialty chemicals organizations to support formulation development, scale-up, and production optimization.
news-medical.net/news/20260511/Uncountable-expands-specialty-chemicals-footprint-with-four-new-deals.aspx
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Scientists discover immune cell control switch to destroy fungal infections
Scientists at the University of East Anglia (UK) have contributed to discovering a "control switch" inside our immune cells that helps the body destroy dangerous fungal infections.
news-medical.net/news/20260511/Scientists-discover-immune-cell-control-switch-to-destroy-fungal-infections.aspx
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Study links mitochondrial health to effectiveness of anti-aging pathways
Mississippi State University biologist Jean-Francois Gout's contributions to a study highlighting key advances in the complexity of aging now are published in Science Advances, a leading peer-reviewed journal of the American Association for the Advancement of Science.
news-medical.net/news/20260507/Study-links-mitochondrial-health-to-effectiveness-of-anti-aging-pathways.aspx
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Building large DNA pieces to create custom microbes
A review in Quantitative Biology demonstrates that scientists can now reliably build and combine very large pieces of DNA, making it much easier to redesign microbes such as yeast and bacteria to act as efficient "cell factories."
news-medical.net/news/20260507/Building-large-DNA-pieces-to-create-custom-microbes.aspx
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Organic lithium salts may affect many cellular level changes in Alzheimer's disease
Lithium chloride may affect many cellular level changes in Alzheimer's disease, a new study from the University of Eastern Finland (UEF) shows.
news-medical.net/news/20260506/Organic-lithium-salts-may-affect-many-cellular-level-changes-in-Alzheimers-disease.aspx
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Obesity and Alzheimer’s linked through early metabolic disruptions
By 2030, the population in the United States aged 65 and older is expected to reach 71 million or about 20% of Americans. This growth is likely to increase the burden of age-related diseases, particularly Alzheimer's disease (AD), affecting about 1 in 9 adults over 65.
news-medical.net/news/20260505/Obesity-and-Alzheimere28099s-linked-through-early-metabolic-disruptions.aspx
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New CAR T cell design boosts persistence and reduces toxicity
CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting benefit – often because the infused cells fail to expand or persist.
news-medical.net/news/20260430/New-CAR-T-cell-design-boosts-persistence-and-reduces-toxicity.aspx
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Cells filter physical forces based on duration to detect disease
Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.
news-medical.net/news/20260429/Cells-filter-physical-forces-based-on-duration-to-detect-disease.aspx
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Study identifies protein essential for repairing damage after inflammation
Whenever there is a wound or infection, the body produces an inflammatory response. This is the body's first line of defense, and macrophages — cells of the innate immune system — play a key role: first, they help eliminate pathogens and other infectious agents, and then they trigger the mechanisms that repair the damage caused during the inflammatory process.
news-medical.net/news/20260428/Study-identifies-protein-essential-for-repairing-damage-after-inflammation.aspx
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NIH awards five year grant for cardiovascular epidemiology training
Boston University Chobanian & Avedisian School of Medicine researchers Vanessa Xanthakis, PhD, FAHA, associate professor of medicine and director of research training, and Mathew Nayor, MD, MPH, associate professor of medicine, have been awarded a five-year, T32 grant from the National Institutes of Health's National Heart, Lung and Blood Institute
news-medical.net/news/20260427/NIH-awards-five-year-grant-for-cardiovascular-epidemiology-training.aspx
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Scientists map 239 human-infective RNA viruses to track future outbreak risks
Researchers updated the global catalogue of human-infective RNA viruses to 239 ICTV-recognised species, incorporating taxonomy, discovery dates, locations, genome links, host range, transmissibility, and transmission routes. The dataset shows that most known human-infective RNA viruses remain strictly zoonotic, while only a minority are endemic in humans or capable of epidemic spread.
news-medical.net/news/20260426/Scientists-map-239-human-infective-RNA-viruses-to-track-future-outbreak-risks.aspx
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New model improves detection of Li-Fraumeni Syndrome risk
In a prospective validation study, researchers at The University of Texas MD Anderson Cancer Center demonstrated that a new mathematical model, called LFSPRO, was effective in supporting genetic counselor decision-making and more accurately predicted individuals at higher risk of Li-Fraumeni Syndrome (LFS), a hereditary condition that carries a higher risk of developing multiple cancers.
news-medical.net/news/20260423/New-model-improves-detection-of-Li-Fraumeni-Syndrome-risk.aspx
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