Stay up-to-date on topics of Internal Medicine including educational cases, guidelines, important research findings. Introduce this channel to your friends interested in Internal Medicine. Contact admin: @aasohrab
3/5
💢 گایدلاین های دیابت به سرعت آپدیت می شوند
... و اندیکاسیون این گروه دارویی گسترده تر می شوند.
🆔 t.me/internalmed
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1/5
💢 داروهای گروه SGLT2i در دهه اخیر یکی از متحول کننده های درمان بیماران دیابتی بوده اند.
در این نمودار، تأییدیه های FDA را می بینید که پشت سر هم در اندیکاسیون های مختلف به این داروها اعطا شدند.
🆔 t.me/internalmed
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ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update
🆔 t.me/internalmed
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💢 The Zollinger–Ellison Syndrome
A 75-year-old man presented to the emergency department with a 6-month history of epigastric pain, watery diarrhea, and weight loss. Physical examination was notable for epigastric tenderness. Esophagogastroduodenoscopy revealed severe esophagitis (Panel A), antral erosions, and duodenal ulcers (Panel B). The gastric pH was below 2, and the fasting serum gastrin level was above 1000 pg per milliliter (reference range, 13-115), findings that established the diagnosis of Zollinger–Ellison syndrome — a syndrome of gastric acid hypersecretion resulting from a gastrinoma. Treatment with a proton-pump inhibitor was initiated, and the patient’s abdominal pain and frequency of diarrheal episodes decreased. Computed tomography with positron-emission tomography identified a single tumor along the fourth part of the duodenum. Surgery with curative intent was performed, which included segmental duodenal resection and lymphadenectomy (Panel C; arrow indicates the tumor). Histopathological analysis showed a well-differentiated neuroendocrine tumor within a lymph node that was positive for gastrin on immunohistochemical staining (Panel D). Three months after the surgery, the fasting serum gastrin level was 44 pg per milliliter, and the findings on esophagogastroduodenoscopy were normal. A tapering of the proton-pump inhibitor dose was started, and the patient’s symptoms did not recur after the proton-pump inhibitor was discontinued.
https://www.nejm.org/doi/full/10.1056/NEJMicm2203797?query=WB
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💢 AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea
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💢 سهم مهم آلودگی هوا در مرگومیر انسانها
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توضیحاتی درباره پست قبلی
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افزودن استازولامید وریدی به دیورتیک های لوپ در رفع احتقان در بیماران با نارسایی قلبی جبران نشده حاد با اورلود موثر است.
🆔 t.me/internalmed
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💢 Monoclonal antibody prevents malaria infection in African adults
https://www.nih.gov/news-events/news-releases/monoclonal-antibody-prevents-malaria-infection-african-adults
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Peripheral Matters | Dose-Reduced Direct Oral Anticoagulants: Practical Considerations
https://www.acc.org/Latest-in-Cardiology/Articles/2022/10/01/01/42/Peripheral-Matters-Dose-Reduced-Direct-Oral-Anticoagulants-Practical-Considerations
💢Threats to Blinding | NEJM Evidence
https://youtu.be/IFLNDmQLgVA
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💢 همه چیز درباره آبله میمون
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2/5
💢 مکانیسم اثر گروه دارویی SGLT2i
ما در دریایی از دیابت و سندرم متابولیک غرقه ایم. نمی شود یک پزشک در این دوران بود و با مفاهیم دیابت و تازه های کنترل آن آشنا نبود.
🆔 t.me/internalmed
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3/3
ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update
🆔 t.me/internalmed
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ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update
🆔 t.me/internalmed
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💢 AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Constipation
🆔 t.me/GIJOURNALCLUB
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Semaglutide 'Gives Hope' to Adolescents With Obesity
The so-called 'gamechanger' obesity injection, semaglutide, is trialed in teenagers with obesity and comes up trumps.
In this trial, adolescents with obesity assigned to weekly subcutaneous semaglutide plus lifestyle intervention had a greater reduction in BMI than those who received lifestyle intervention alone.
2022 guideline for perioperative management of VKAs, heparin bridging, DOACs & antiplatelets
Читать полностью…💢 سرعت پیشرفت از کبدچرب تا سیروز، در همه سنین مشابه است
https://www.medscape.com/viewarticle/983339?src=rss#vp_1
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توجه شما را به نکاتی در پیام صوتی بعدی جلب می کنم
👇👇
💢 Pharmacotherapy for Nonalcoholic Fatty Liver Disease Associated with Diabetes Mellitus Type 2
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https://jamanetwork.com/journals/jama/fullarticle/2798011
Читать полностью…ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update
Читать полностью…A 37-year-old man presented to the emergency department with a 1-week history of pain and swelling in the left upper arm that had started after blunt trauma to the arm during a soccer practice. He had a history of opioid use disorder, which had been treated with buprenorphine. He reported no intravenous drug use during the past 2 years. The heart rate was 120 beats per minute, the blood pressure 96/54 mm Hg, and the body temperature 37.9°C. Examination of the left upper arm was notable for swelling, tenderness, and crepitus. The overlying skin was red and warm to the touch. A radiograph of the upper arm showed radiolucent areas with air–fluid levels in deep tissue. Subsequent computed tomography of the upper arm revealed pockets of gas in the muscles of the extensor compartment. Owing to concern about necrotizing myositis, emergency surgical débridement was performed, and the diagnosis of necrotizing myositis was confirmed. In patients with necrotizing myositis, plain radiographs may show only soft-tissue edema, unlike the radiographic findings in this case. Clinicians should have a high index of suspicion for this life-threatening condition in patients with focal, progressively worsening muscle pain and systemic symptoms. A second débridement was performed 48 hours after the initial surgery. After 3 weeks of broad-spectrum antimicrobial therapy to treat a polymicrobial infection, the patient’s condition improved, and he regained function of his arm.
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