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Telegram-канал pythonofftopic - Offtopic

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Offtopic group for casual talking about anything. @rules_for_python still apply (except for the ontopic rule)

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But if your HDD will need to be reformatted

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Legasy means mbr bios.but i think it is gpt.and my bootable USB is uefi based.so this is not a problem

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Hope i'm not beeing boring ya'll

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I summarized it for you @JavaOfftopic

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It's ok, that's fine

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@fbrond, can i send you info ?

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Always remember, DMN is not the right or wrong perception, it's only one of the perceptions of reality you can feel. Search about it and you'll see

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In a certain point of view

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Honestly, i think your right

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hi, and i am a primitive species here

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If I don't have the possibility or pay university fees, can I learn data science through self-education?

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How you ended here whithout beign part of the ontopic groups?

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I will look it up, thanks

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telegram offers some payment methods that involve crypto

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consider using telegram

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Go into bios and disable csm/legacy mode

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I used Rufus and i have asus motherboard.today i started my pc.and and my windows got hanged.then i restart it.and it was unable to start now because of some missing dlls.then i attach my bootable usb and got this error.but i previously installed windows several time with this same bootable usb.i did some researched on this.and i found that i have to clean my hardisk for proper installation

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🧠 Psychedelics & the Brain: A Neuroscience Overview
1. Default Mode Network (DMN) – The Brain’s Baseline Narrative
The DMN includes the medial prefrontal cortex (mPFC), posterior cingulate cortex (PCC)/precuneus, angular gyrus, and hippocampus. It’s most active during self-referential thought, mind-wandering, and internal narration
→ Psychedelics disrupt the DMN, correlating with:
Ego-dissolution
Decreased rumination
Emotional openness
Altered sense of time and self
🔗 PubMed, PubMed, Frontiers

2. Network Rebalancing – Cross-Talk & Functional Connectivity
When DMN activity decreases, connectivity across brain networks increases, especially between:
Salience Network (SN)
Task-Positive Network (TPN)

This shift enhances:
Sensory awareness
Emotional salience
Inter-network fluidity

→ Under psilocybin, DMN-TPN cross-connectivity increases—blurring boundaries between introspection and external attention.
🔗 PubMed

3. Thalamus – The Gatekeeper of Perception
The thalamus filters and relays sensory information to the cortex. Psychedelics disrupt this filter:

LSD increases thalamocortical connectivity, especially with sensory & DMN regions → Sensory overload and blending
Psilocybin alters thalamic connections with visual and self-related networks

→ More “raw” information floods through—less filtered by habitual cognitive hierarchies.
🔗 Wikipedia, AJNR, Frontiers

4. DMT & Neuroplasticity
DMT acts strongly at 5‑HT₂A receptors, disrupting DMN activity and boosting global brain connectivity.

Animal and cell studies show DMT also promotes:
Dendritic growth
New synapse formation (synaptogenesis)
Anti-inflammatory gene expression

→ Suggests potential for long-term neural rewiring and healing.
🔗 Vox, MDPI

5. Thalamocortical Resonance & Consciousness
The thalamocortical oscillation hypothesis suggests synchronized rhythms between thalamus and cortex help bind together our unified sensory experience.

→ Psychedelics disrupt this resonance, potentially uncoupling perception from language-driven meaning and allowing more direct, unstructured experiences.
🔗 Wikipedia

🎯 Conceptual Integration
• The DMN = your internal “you-narrative” (memory, language, culture)
• The thalamus = filters sensory input → constructs "reality"
Psychedelics turn down the DMN + loosen thalamic filters → more bottom-up data floods the system
• What breaks through is “the It”—an unsymbolized, raw experience outside of typical conceptual frameworks

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I promise i'll stop talking

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Please, don't take me wrong, i just wanna spread knowledge

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Thalamus will reduce the actual objective reality, so we are never really in touch with it... Our brain is just used to DMN

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Stay safe in home, away from traffic while doing dmt. 👍

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It may be too much too handle it for some people

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I wanna be many things none of them is being 🥜s

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Hi definitely real person

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I saw the preview before joining, seems I cant chit chat there so found the pinned message and came here

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Yes this is exactly to learn and deepen continuously this is beauty

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now i dont know if telegram can act as a gateway

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People in other group say that Cryptomus is not bad

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And I was hoping to get some recommendations

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