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Offtopic group for casual talking about anything. @rules_for_python still apply (except for the ontopic rule)
Legasy means mbr bios.but i think it is gpt.and my bootable USB is uefi based.so this is not a problem
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Always remember, DMN is not the right or wrong perception, it's only one of the perceptions of reality you can feel. Search about it and you'll see
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If I don't have the possibility or pay university fees, can I learn data science through self-education?
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How you ended here whithout beign part of the ontopic groups?
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telegram offers some payment methods that involve crypto
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I used Rufus and i have asus motherboard.today i started my pc.and and my windows got hanged.then i restart it.and it was unable to start now because of some missing dlls.then i attach my bootable usb and got this error.but i previously installed windows several time with this same bootable usb.i did some researched on this.and i found that i have to clean my hardisk for proper installation
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🧠 Psychedelics & the Brain: A Neuroscience Overview
1. Default Mode Network (DMN) – The Brain’s Baseline Narrative
The DMN includes the medial prefrontal cortex (mPFC), posterior cingulate cortex (PCC)/precuneus, angular gyrus, and hippocampus. It’s most active during self-referential thought, mind-wandering, and internal narration
→ Psychedelics disrupt the DMN, correlating with:
• Ego-dissolution
• Decreased rumination
• Emotional openness
• Altered sense of time and self
🔗 PubMed, PubMed, Frontiers
2. Network Rebalancing – Cross-Talk & Functional Connectivity
When DMN activity decreases, connectivity across brain networks increases, especially between:
• Salience Network (SN)
• Task-Positive Network (TPN)
This shift enhances:
• Sensory awareness
• Emotional salience
• Inter-network fluidity
→ Under psilocybin, DMN-TPN cross-connectivity increases—blurring boundaries between introspection and external attention.
🔗 PubMed
3. Thalamus – The Gatekeeper of Perception
The thalamus filters and relays sensory information to the cortex. Psychedelics disrupt this filter:
• LSD increases thalamocortical connectivity, especially with sensory & DMN regions → Sensory overload and blending
• Psilocybin alters thalamic connections with visual and self-related networks
→ More “raw” information floods through—less filtered by habitual cognitive hierarchies.
🔗 Wikipedia, AJNR, Frontiers
4. DMT & Neuroplasticity
DMT acts strongly at 5‑HT₂A receptors, disrupting DMN activity and boosting global brain connectivity.
Animal and cell studies show DMT also promotes:
• Dendritic growth
• New synapse formation (synaptogenesis)
• Anti-inflammatory gene expression
→ Suggests potential for long-term neural rewiring and healing.
🔗 Vox, MDPI
5. Thalamocortical Resonance & Consciousness
The thalamocortical oscillation hypothesis suggests synchronized rhythms between thalamus and cortex help bind together our unified sensory experience.
→ Psychedelics disrupt this resonance, potentially uncoupling perception from language-driven meaning and allowing more direct, unstructured experiences.
🔗 Wikipedia
🎯 Conceptual Integration
• The DMN = your internal “you-narrative” (memory, language, culture)
• The thalamus = filters sensory input → constructs "reality"
• Psychedelics turn down the DMN + loosen thalamic filters → more bottom-up data floods the system
• What breaks through is “the It”—an unsymbolized, raw experience outside of typical conceptual frameworks
Please, don't take me wrong, i just wanna spread knowledge
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Thalamus will reduce the actual objective reality, so we are never really in touch with it... Our brain is just used to DMN
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Stay safe in home, away from traffic while doing dmt. 👍
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I saw the preview before joining, seems I cant chit chat there so found the pinned message and came here
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Yes this is exactly to learn and deepen continuously this is beauty
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