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Pancreatic cancer progression is driven by glutamatergic pseudo-synapses between sensory neurons and tumor cells, where glutamate activates and increases expression of GRIN2D NMDA receptors. More NMDA pores generate larger calcium signaling that enhances malignant behavior.
https://www.cell.com/cancer-cell/abstract/S1535-6108(25)00395-2

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African Americans, women, rural dwellers and less-educated people are more likely to distrust scientists. They’re also less likely to be scientists. That’s not a coincidence, new research found.
https://news.northeastern.edu/2025/12/09/science-representation-northeastern-survey/

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Reciprocity drives support for climate action—citizens in China, India, Japan and the United States were more willing to back ambitious climate policies when they believed other countries were making substantial efforts of their own, according to a survey of 4,000 respondents.
https://journals.plos.org/climate/article?id=10.1371/journal.pclm.0000755

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Humans rank above meerkats but below beavers in monogamy league table. Human beings in 7th place out of 35 species on monogamy scale, according to a study by Cambridge University.
https://www.theguardian.com/science/2025/dec/10/humans-rank-among-leading-monogamous-mammals-study-finds

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Scientists reveal TY1 — the first synthetic RNA drug able to trigger DNA repair and revive damaged tissue — opening new possibilities for recovery after heart attacks and for treating autoimmune and inflammatory diseases as a new era of exomer therapeutics emerges.
https://www.science.org/doi/10.1126/scitranslmed.adp1338

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Not having offspring key to long life: research shows blocking reproduction can increase the lifespan of males and females of 117 different mammal species. In males, only castration extends lifespan — not vasectomy. In females, lifespan increased after several different forms of sterilisation.
https://www.nature.com/articles/s41586-025-09836-9

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Humans made fire 350,000 years earlier than previously thought. The control of fire provided warmth, light, protection from predators, and allowed humans to process a wider range of foods, supporting better survival, larger groups and freeing up energy to fuel brain development.
https://www.theguardian.com/science/2025/dec/10/man-made-fire-350000-years-earlier-than-previously-known-after-discovery-in-suffolk

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Huge genetic study reveals hidden links between psychiatric conditions. A genomic analysis of more than one million people suggests that a most major psychiatric conditions have common biological roots.
https://www.nature.com/articles/d41586-025-04037-w

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Glyphosate safety article retracted eight years after Monsanto ghostwriting revealed in court
https://retractionwatch.com/2025/12/04/glyphosate-safety-article-retracted-elsevier-monsanto-ghostwriting/

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People who identify as politically conservative are more likely than their liberal counterparts to find “slippery slope” arguments logically sound. This tendency appears to stem from a greater reliance on intuitive thinking styles rather than deliberate processing.
https://www.psypost.org/conservatives-are-more-prone-to-slippery-slope-thinking/

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Antarctica's only native insect is already ingesting microplastics, even in one of the planet's most remote regions. In Belgica antarctica, ingestion was rare and non-lethal, yet larval exposure reduced lipid stores in a dose-dependent manner, confirming contamination in natural habitats.
https://www.sciencedirect.com/science/article/abs/pii/S0048969725024404?via%3Dihub

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Cancer cells become more aggressive as they increasingly rely on glycolysis and glycolytic waves, rather than mitochondrial ATP which is the normal energy-generation process, to supply the local ATP needed for invasion and nutrient uptake.
https://www.nature.com/articles/s41467-025-60596-6

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People who read right-leaning tabloid papers more often showed stronger negative automatic biases towards autism. People’s newspaper reading habits are a reliable predictor of their attitudes towards autism, even when many other factors such as age, education, political views and personal experience
https://www.citystgeorges.ac.uk/news-and-events/news/2025/december/link-between-newspaper-preference-and-attitudes-towards-autism

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Malaria-carrying mosquitoes are rapidly developing resistance to Actellic 300S, a key new-generation insecticide in control programs. A new study warns this surge could undermine global efforts to contain the disease and put millions, especially young children, at risk.
https://www.nature.com/articles/s41467-025-65827-4

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"Forever chemicals" (PFAS) that contaminate drinking water in cities across the U.S. impose annual social costs of at least $8 billion
https://news.arizona.edu/news/new-research-links-health-impacts-related-forever-chemicals-billions-economic-losses

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People blink less when they are working harder to understand speech in noisy environments, suggesting that blinking reflects the mental effort behind listening, while blink patterns remain stable across different lighting conditions
https://www.concordia.ca/cunews/stories/2025/12/09/blinking-less-could-signal-the-brain-is-working-harder-to-listen-concordia-study-shows.html

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Orcas team up with dolphins to hunt salmon, study finds | Northern resident killer whales appear to use dolphins as ‘scouts’, in a surprising cooperative hunting strategy
https://www.theguardian.com/environment/2025/dec/11/orca-killer-whale-dolphin-hunt-salmon-study-british-columbia-canada

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Anxiety and insomnia have been shown to weaken the immune system and make us more prone to disease. New findings showed that in young women, experiencing insomnia or anxiety symptoms can reduce the number of natural killer cells, our bodies’ machinery for defense.
https://www.frontiersin.org/news/2025/12/10/anxiety-insomnia-natural-killer-cell-immune-function

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Most of the world’s population carries the H1 haplotype at chr17q21.31. A new study shows H1 neurons are more vulnerable than H2 neurons to ferroptosis, an iron-mediated ROS cell death mechanism linked to Alzheimer’s, Parkinson’s, ALS, Lewy body dementia, PSP, and corticobasal degeneration.
https://www.nature.com/articles/s41419-025-08147-1

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New mapping reveals how Narcan reverses opioid overdose, providing a molecular blueprint for more effective drugs.
https://dornsife.usc.edu/news/stories/how-does-narcan-work/

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Breastfeeding while taking antidepressants does not affect a child's IQ, a long-term study finds. Tracking 97 mother–child pairs for nearly two decades — all exposed to SSRIs in utero — researchers saw no difference in verbal or performance IQ. Breastfed children scored similarly to those unexposed.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2841745

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In February 2025, Trump blocked future enforcement of the Foreign Corrupt Practices Act (FCPA), which had made it unlawful for US companies to bribe foreign public officials. The announcement led to a substantial boost in the stock value of firms linked to corrupt practices.
https://www.cambridge.org/core/journals/international-organization/article/making-bribery-profitable-again-the-market-effects-of-suspending-accountability-for-overseas-bribery/D21C274479ACBEC62F58E10BEFC257FB

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Scientists Thought Parkinson’s Was in Our Genes. It Might Be in the Water
https://www.wired.com/story/scientists-thought-parkinsons-was-in-our-genes-it-might-be-in-the-water/

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Consuming lots of energy drinks may raise heart disease and stroke risk. A fit and healthy man in his 50s had a stroke and was left with permanent numbness in his hands and feet. He drank an average of 8 energy drinks a day, totaling 1,200mg of caffeine. The recommended maximum intake is 400mg.
https://www.theguardian.com/society/2025/dec/09/energy-drinks-heart-disease-stroke-risk-doctors

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A nationwide study found that ketamine does not improve survival compared with etomidate and carries a higher risk of heart-related complications during emergency intubation. The findings provide long-awaited evidence to guide one of the most critical decisions emergency clinicians make.
https://news.cuanschutz.edu/news-stories/national-trial-ketamine-raises-heart-risk-no-survival-advantage-over-etomidate-in-emergency-intubation

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Violence against women and children among top health threats: New global study reveals disease burden far larger than previously estimated
https://www.eurekalert.org/news-releases/1108985

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Supportive marriage linked to lower obesity risk through novel brain-gut pathway: high-quality marital bonds are associated with lower body mass index and healthier eating behaviors, potentially regulated by the hormone oxytocin and its interaction with the microbiome.
https://www.psypost.org/supportive-marriage-linked-to-lower-obesity-risk-through-novel-brain-gut-pathway/

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Early IPCC estimates of sea level rise turned out to be stunningly precise. Decades ago scientists projected roughly eight centimetres without today’s modelling power and real-world measurements now show nearly nine as oceans continue their steady climb.
https://agupubs.onlinelibrary.wiley.com/doi/10.1029/2025ef006533

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Scientists in Pompeii found construction materials confirming the theory about how Roman concrete was made
https://www.zmescience.com/science/archaeology/pompeii-roman-concrete-hot-mixing-secret/

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Children exposed to higher-than-usual temperatures —average maximum above 86 °F (30 °C)—were less likely to meet developmental milestones for literacy and numeracy, relative to children living in areas with lower temperatures
https://www.nyu.edu/about/news-publications/news/2025/december/-excessive-heat-harms-young-children-s-development--study-sugges.html

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