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🔴The fetal components that contribute to these tissues are not strongly antigenic,

➡️ they form a barrier that keeps the fetus isolated in its own antigen-free environment.

⭕The placenta is surrounded by a dense, many- layered envelope that prevents the passage of maternal cells, and it actively
absorbs,
removes,
+ inactivates circulating antigens.

#د_طالب

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ممكن يجيبة كتعداد يكلك
Application of monoclonal antibodies
الجواب :
1..targeting growth factor receptor ( anti-HER2)
2..targeting tumor vasculature ( anti-VEGF)
3..immune mediated ADCC/CDC/CAR-T
4..immune checkpoint inhibition ( anti-PD1 , anti-PD-L1 , anti CTLA4)
5..bispecific antibodues
6..bdelivery of payloads

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"أرح عقلك واتركها تأتي كما كتبها الله.

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Gram positive :

GspB SRRp = S. gordonii

Sortase assembied pilus = C diphtheriae


✨✨✨✨

Gram negative


Type IV pilus : N gonorrhoes

Curli : S enterica

YadA TAA : Y enterocollica

Type 1 pilus : E coli

FimA fimbriae : P gingivalis

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MCQ/Gram-positive streptococci Lec 1

الأجوبة الصحيحة تحتها خط

#د_فاتن

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محاضرة mycobacteria
الاشياء والاسئلة الذكرهه دكتور بالمحاضرة

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Intracellular pathogens

🍃M.Tuberclosis
🍃Legionella
🍃Listeria
🍃Brucellea

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To prevention of tetanus:

1-Active immunization with tetanus toxoid.
2-Proper care of wounds contaminated with soil.
3-Prophylactic use of antitoxin.
4- Administration of penicillin.


#د_سعد
#مرشح 💀

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+اقروا للاسي للواضح + لان ممكن الدكتور يجيب كيس مثلا ويسال عليه .

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#مجزرة_الفراغات_الفصل_الاول

#د_زينب

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د زينب جابت فرغات
1-Three gram positive bacteria in esophagus ........... , ........... and .........

2-bacteria ........... product ........... and ......... to evade phagocytosis

3-Blood culture is ........ to isolation ....


4-Enterotoxin product by ........

5-Plaque infected with....... tetanus infected with .......


6- Y enterocolitica product ........ pili, while GspB SRRP pili product by ........

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HSV-1 affects most commonly the trigeminal ganglion,
HSV-2 affects the sacral nerve root ganglion.

للتذكر Sacral N➡️Second

#د_انتظار

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#اسئلة

عن محاضرة Legionella species disease مهمات

#د_زينب

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Different btween Legionnaires’ disease and “Pontiac fever”

#ملاحظة_افتح الصورة لباقي المقارنة

تفيدكم كيسات ومراجعة

#د_زينب
#مرشح

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Diagnosis of Listeriosis?
اگدر اختصره ب بكلمه مسج
MCG

1-M (monocytosis )/
Peripheral blood + cerebrospinal fluid

2- C(culture )
Blood

3-G(gram stian)
G+rod in CSF.

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All of the following type of bacteria invade specific types of the host’s
epithelial cells and may subsequently enter the tissue:

Yersinia species
N gonorrhoeae
Chlamydia trachomatis


While
invade tissues through the junctions between epithelial cells Salmonella species
#د_زينب

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الكل تدرس وتنسى مو بس انت وهذا شي نورمل بسبب كمية المعلومات واغلبها مترابطة .

عليك تكمل وتتوكل على الله واترك الافكار السلبية بس تاخذ منك وقت.


#نصيحة

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هاي توضيح مال

#مجزرة_الفراغات_الفصل_الاول

#د_زينب

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مهم حفظ
جابت منة بالامتحان

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MCQ/Gram-positive streptococci Lec 1

اسئلة مهمه محاضرة دكتورة فاتن الاولى

1️⃣.In a patient of orbital cellulitis, micro organism on
culture show greenish colonies and optochin sensitivity.
The most likely organism is :
a) Strep. viridans
b) Staphylococcus
c) Pseudomonas
d) Pneumococcus


2️⃣.True statement regarding Pneumococcus is :

a) Virulence is due to polysaccharide capsule
b) Capsule is protein in nature
c) Antibodies against capsule are not protective
d) Resistance to penicillin has not yet been reported


3️⃣.Lance field grouping of streptococci is done by using :
a. M protein
b. Group C peptidoglycan cell wall
c. Group C carbohydrate antigen
d. M antigen


4️⃣.An infant had high grade fever and respiratory distress
at the time of presentation to the emergency
room. The sample collected for blood culture was
subsequently positive showing growth of αhemolytic
colonies. On Gram staining these were
gram positive cocci. In the screening test for identification,
the suspected pathogen is likely to be
susceptible to the following agent :
a) Bacitracin
b) Novobiocin
c) Optochin
d) Oxacillin

5️⃣.Streptococcal toxic shock syndrome is due to the
following virulence factor : [AIIMS 03]
a) M protein
b) Pyrogenic exotoxin
c) Streptolysin O
d) Carbohydrate cell wall


6️⃣.The commonest organism causing cellulitis is :
a) Streptococcus pyogenes
b) Streptococcus faecalis
c) Streptococcus viridans
d) Microaerophilic streptococi

7️⃣.Lymphangitis is caused by:
a) Staphylococcus
b) Streptococci
c) Pneumococci
d) Neisseria

8️⃣.Streptococci causing dental caries:
a) Streptococci equisimilis
b) Streptococci mutans
c) Streptococci pneumoniae
d) Streptococci bovis

9️⃣.Streptococcus and pneumococcus differentiated all of the following except:
a) Bile salt solubility
b) Growth charcteristic
c) Gram staining
d) Inulin fermentation

🔟.C-Carbohydrate in Streptococcus hemolyticus is important for:
a) Lancefield classification
b) Phagocytic inhibition
c) Toxin production
d) Haemolysis

11.Which toxin of streptococcus causes hemolysis:
a) Streptolysin O
b) Sterptolysin S
c) Streptokinase
d) Sterptodornase

#د_فاتن

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Prevention and Control of mycobacteria tuberculosis
بصورة اسهل ومختصرة لان بالمحاضرة مطولة
..


1.Prompt and effective treatment of active tuberculosis patients, along with follow-up of their contacts, is crucial to control the spread of tuberculosis.

2.Treating asymptomatic tuberculin-positive individuals with drug therapy reduces reactivation of the infection.

3.Factors that reduce host resistance, such as starvation, gastrectomy, and immune suppression, increase the risk of developing tuberculosis. HIV infection is a significant risk factor for tuberculosis.

4.Vaccination with BCG can induce resistance to tuberculosis, but available vaccines have limitations.

5.Eradication of tuberculosis in cattle and pasteurization of milk have greatly reduced M bovis infections.

#د_سعد

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ملخصات للاغلب المواضيع 💀

#مايكرو

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نقصد هيج 💀

Germination of the spore and development of vegetative organisms that produce toxin C tetani are aided by :
(1) necrotic tissue,
(2) calcium salts,
(3) associated pyogenic infections,

#د_سعد

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بالنسبة لمادة دكتور سعد
الافضل تركزون على تفاصيل واضحة وليس تقرؤوها بشكل سَردي ..وكذلك كل نوع من البكتيريا تعودون للكيسات تطلعون على الاسئلة ..

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نقطة جايبتة من هذا رسم
د زينب

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ملخص للاهم للأشياء للمحاضرات الفصل الاول دكتورة زينب هم شوفوهم منا تبلش

#د_زينب
#فصل_اول

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Classification of Herpesvirus into three subfamilies based on

علمود نتذكرهم نختصرهم VPC

viral characteristics,
pathogenesis of the disease,
clinical manifestation of the disease.



1-The α herpesviruses, herpes simplex virus types 1 and 2, and varicell azoster virus
2-β herpesviruses, cytomegalovirus, and human herpesviruses 6 & 7,

3- γ herpesviruses, Epstein-Barr virus and human herpesvirus 8,

اتذكرو γ herpesviruses فقط للانواع للتسبب او مرتبطة ب cancer

#مرشح #مرشح #مرشح 💀

#د_انتظار

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Different btween Legionnaires’ disease and “Pontiac fever”

#ملاحظة_افتح الصورة لباقي المقارنة

تفيدكم كيسات ومراجعة+ من كلام الملزمة نصا على شكل مقارنة .

#د_زينب
#مرشح

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Treatment of Listeria :

Ampicillin , erthromycine and intravenous trimethoprim - sulfamethaxzole .

The cephalosporin and fluoroqiunolones are not active against l.monocytogenes.

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Cephalosporins and fluoroquinolones are not active against L monocytogenes.

علمود لا ادوخون هذا ج

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