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Correct Answer - B
Ans. B. Reverse Koebner's phenomenon
[Refhttps://www.researchgate.net/publication/268343496_Proposed_
classification_for_koebner_wolf
isotopic_renbok_koebner_nonreaction_isotopic_nonreaction_other_relatedphenomen]
Annular orange skin lesions in a diabetic indicate towards granuloma annulare.
There have been few reports of disappearance of lesions after
biopsy in granuloma annulare.
This phenomenon is known as reverse Koebner's phenomenon.
@dermatology_vid
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Ans. A.Cold temperature
Cutis marmorata is a condition where in the skin has a pinkish blue mottled or marbled appearance when subjected to cold temperatures.
It is seen throughout infancy and in 50 % of children.
Rewarming restores the skin to normal.
It is caused by superficial small blood vessels in the skin dilating and contracting at the same time .
@dermatology_vid
Correct Answer - C
Ans. C. Popliteal fossa
Sites of itching patch in atopic dermatitis Infant; Face (especially cheek), extensors offorearm& legs.
Childhood & adult > Flexures (antecubitalrbitalfoxa,Poplitealfossa).
@dermatology_vid
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Correct Answer - B
Ans. B. Stratum granulosum
Odland bodies are membrane coated granules in stratum
granulosum, which contain lipids which is responsible for barrier
function of this layer.
This layer also contains diamond shaped keratohyaline granules,
which are the characteristic features of this layer.
These keratohyaline granules contain filaggrin protein which is
responsible for aggregation of keratin filaments.
@dermatology_vid
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Correct Answer - D
Ans. D. Lichen planus
LP is characterized by shiny, violaceous, flat-topped polygonal
papules which retain the skin lines.
White lines, known as Wickham's striae, may traverse the surface of
the papules.
Linear lesions often appear along scratch marks or in scars
(Koebner phenomenon).
In most cases, the papules eventually flatten after a 6 months to 2 yrs, often to be replaced by an area of hyperpigmentation.
@dermatology_vid
Correct Answer - B
Ans. is B' i.e., Herpes genitalis
Herpes genitalis is a sexually transmitted disease, characterized by appearance of multiple painful vesicles in clusteres in genital area
which later on may ulcerate. These small ulcers may combine to
form a large ulcer. First attack of this in infection may be associated
with flu like symptoms but GIT symptoms are usually absent.
Gonorrhea is characterized by acute anterior arthritis associated
with thick yellow urethral discharge. Perianal ulceration is not a
feature of gonorrhea.
Although HIV can be considered in the differential diagnosis of
Perianal ulcers, but is usually associated with GIT symptoms.
Perianal ulceration is not a feature of CMV infection
@dermatology_vid
Correct Answer - A
Ans. is 'a' i.e., Atopic dermatitis
Hanifin and Rajka criteria is for diagnosis of atopic dermatitis.
Diagnostic criteria (Hanifin and Rajka)
Based mainly on clinical experience
Major criteria
1. Family history of atopy
2. Chronicity
3. Pruritus
4. Typical morphology and distribution
Minor criteria
1. Dry skin
2. Chelitis
3. Elevated edge
4. Dennie's line/dennie morgan fold (infra orbital fold)
5. White dermographism
6. Peripheral eosinophillia
7. Immediate (type i) hypersensivity
8. Facial pallor, orbital darkening
9. Food intolerance
10. Conjunctivitis (recurrent), keratoconus, cataract
11. Pityriasis albaHand dermatitis
13. Recurrent infections
At least 3 major or 2 major plus 2 minor criteria are necessary for
diagnosis
@dermatology_vid
Correct Answer - D
Ans. is 'd' i.e., All of the above
Acanthosis nigricans
Acanthosis nigricans is a brown to black, velvety hyperpigmentation
of the skin. It is usually found in body folds, such as posterior &
lateral folds of neck, axilla, groin, umblicus, forehead. It typically
occurs in individuals younger than 40 years of age.
Histopathologically papillomatosis is characteristically seen;
however, there is no hypermelanosis and there is only mild
acanthosis, if present.
It is associated with
1. Obesity (most common)
2. Endocrinopathies —> Hypothyroidism, hyperthyroidism, insuline
resistance diabetes, Cushing's disease, PCOD, Bloom syndrome.
3. Internal malignancy —> Gastric adenocarcinoma
@dermatology_vid
Correct Answer - C
Ans.C.Spinosum and basale
The Malpighian layer of the skin is generally defined as both the
stratum basale and stratum spinosum as a unit, although it is
occasionally defined as the stratum basale specifically,or the stratum
spinosum specifically. It is named after Marcello Malpighi.
@dermatology_vid
Correct Answer - C
Ans. is 'c' i.e., Clubbing
Clinical indicators of clubbing are
Lovibond profile sign and
curth's modified profile sign".
Lovibond angle is the angle located at the junction between the nail
plate and proximal nail fold. It is normally less than 160°.
In clubbing, the angle exceeds 180° (Lovibond profile sign).
@dermatology_vid
Correct Answer - A
Ans. is 'a' i.e., Hydroquinone
Skin depigmenting agents in clinical use are
Hydroquinone - most effective and widely used
Kojic acid
Kojicdipalmitate
Azelaic acid
@dermatology_vid
Correct Answer - A
Ans. A. Penicillamine
Drugs causing pemphigus
Penicillamine
Penicillins and Cefalosporins
Captopril,
Iodine,
Lithium
Phenophthelin,
Propanolol
Rifampicine
Phenytoin,
Phenylbutazone,
Salicylates,
Piroxicam,
Sulphonamides
@dermatology_vid
Correct Answer - C
Ans. C. Post inflammatory hypomelanosis
[Ref IADVL 3"1/e p. 747-748]
Among given options, postinflammatory hypomelanosis is the best answer.
understand let us have a look at the definition few important terms.
Vitiligo is also an acquired condition with loss of pigmentation but most cases are idiopathic.
It is mainly considered to be an autoimmune condition.
Precipitated by hormonal changes, acute emotional trauma or stress
or any condition leading to immune imbalance.
So, any hypomelanosis resulting after inflammation is known as post inflammatory hypomelanosis (including leucoderma).
Sometimes both the terms are used synonymously.
Whereas the term 'chemical leucoderma' is used only when there repeated exposure (contact) to some specific chemical.
Therefore among given options, postinflammatory hypomelanosis is the best answer as drug reaction is an inflammatory condition
leading to residual hypopigmentatio
@dermatology_vid
Correct Answer - B
Ans. B. Acanthosis
[Ref Rook's 7th/e p. 7.36]
Important terminology related to epidermal layers Separation of keratinocytes due to loss of intracellular bridges - Acantholysis
Intracellular edema of keratinocytes Ballooning
@dermatology_vid
Correct Answer - A
Ans.A. Keratinocyte
Tzank cells are acanthoylytic cells i.e. large rounded keratinocytes
with relatively large nucleus with condensed or hazy cytoplasm.
@dermatology_vid
Correct Answer - B
Ans. B. Polyhedral
5 characteristic 'P’ of lichen planus
1. Pruritic (itching)
2. Polygonal
3. Purple (violaceous)
4. Plane (flat topped)
5. Papule or plaque
These 5 Ps are the characteristic features of lichen planus lesions
presentation.
@dermatology_vid
Correct Answer - A
Ans. A. 2%
[Ref IADVL 3'/e p. 891]
In female androgenic alopecia results are similar with 2% and 5%
minoxidil but side effects are more with 5% solution.
Whereas in males 5% is more efficacious.
Therefore in a female patient 2% minoxidil is preferred whereas in
males 5% solution is the preferred choice.
@dermatology_vid
Correct Answer - D
Ans. D. Subdermal
@dermatology_vid
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Correct Answer - C
Ans. C. Histologically there is hypermelanosis
Acanthosis nigricans is brown to black discolouration which usually
affects body folds like axilla, groin, umblicus, forehead.
Acanthosis nigricans occurs in individuals younger than 40 years of age.
It is associated with obesity (most common); endocrinopathy like
insulin resistance DM, hypothyroidism, Bloom synd., PCOD, and internal malignancy e.g. gastric adenocarcinoma.
Histopathologically, Papillomatosis is the characteristic feature
whereas there is no hypermelanosis.
@dermatology_vid
Correct Answer - A
Ans. is 'a' i.e., Keratin
Dermatophytes are keratinophillic fungi, living only on the superficial
dead keratin. That is why they infect skin, hair and nail. In skin they
infect most superficial layer of the epidermis i.e. stratum corneum.
They do not penetrate living tissues. Dermatophytes cause a variety
of clinical conditions, collectively known as dermatophytosis, tinea or
ringworm. Dermatophytes have been classified into 3 genera :-
trichophyton, microsporum, epidermophyton.
1. Trichophyton affects;- skin, hair, nails
2. Microsporum affects ;- skin, hair (nails are not affected)
3. Epidermophyton affects:- skin, nails (hair are not affected)
Deep fungal infections (eg:- maycetoma, chromoblastomycosis,
pheohyphomycosis, sporotrichosis, lobomycosis, rhinosporidiosis)
involve subcutaneous tissue.
Dermatophytosis is itchy and scaly
@dermatology_vid
Correct Answer - A
Answer- a. Lamellar ichthyosis
Explanation- Ichthyosis is one of the most commongenodermatoses. It is characterized by dry (xerotic) scaly skin all over the body. Scales are dull-brown-black.
The basic defect is an impairment in the barrier function of skin and
inability to maintain moisture. Collodion baby is the term used to
denote the newborn baby with ichthyosis; the newborn baby is
encased in a thick, shiny membrane coat called collodion and is
seen in Lamellar ichthyosis
Ref- Arvind Arora skin, 6th edition, page no 203
@dermatology_vid
Correct Answer - C
Ans. is 'c' i.e., Stratum corneum
Stratum basale, stratum spinosum and stratum granulosum,
together form the living layer and constitute the site of synthesis of
keratin
(Keratin is mostly synthesized in stratum spinosum).
Stratum corneum is the dead layer.
Layers of epidermis (From deep to superficial)
In palm and sole( 5layers)
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum
Stratum corneum
Elsewhere (4layer)
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum corneum
@dermatology_vid
