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Hey newbeezz!!!
I know there's so much to learn but isn't fun...
Okay so I guess in the childhood we all have heard the song, Baby.. Yeah that same which you tried to sing but for someone... .Ok let's not go that way...
So yeah the singer justin bieber is suffering from a condition ----------- which affects------- nerve....

A) bell's palsy, VIIth nerve
B) Bell's palsy, VIIIth nerve
C) Ramsay hunt syndrome, VIIIth nerve
D) Ramsay hunt syndrome, VIIth nerve
E) Sir, mujhe koi mili hi nhi...

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Dermatology

PGI PG CHANDIGARH 2009

Q.]During acclimitisation, decreased sweating is due to down regulation of?

a) Epinephrine receptors

b) Norepinephrine receptors

c) Acetylcholine receptors

d) Dopamine receptors

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Dermatology

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Correct Answer - C
Ans. C. Hard Chancre
Characteristics of various different types of genital ulcers -

Primary syphilis (hard chancre) :- punched out, painless, nonbleeding(avascular) ulcer with 6rm induration.

Donovanosis :- one or more, painless, bleeding (vascular) ulcers
with induration.

Chancroid (soft chancre):- multiple, painful, bleeding (vascular)ulcers with no or soft induration.

LGV: - single, painless, non-bleeding ulcer.
Herpes genitalis: - multiple painful/asymptomatic ulcers.

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Dermatology

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Dermatology

Correct Answer - A
Ans. A. Remain constant throughout life time of a person
[Ref: IADVL text book of dermatology 3rd le p. 175 & Internet]
Langer's lines

Also called cleavage lines, is a term used to define the direction
within the human skin along which the skin has the least flexibility.

These lines correspond to the alignment of collagen fibers within the dermis.

Usually, a surgical cut is carried out in the direction of langer's lines,
and incisions made parallel to langer's lines generally heal better
and produce less scarring.

Directional changes of Langer's lines have been known to occur
within the course of a person's lifetime.

Sometimes the exact direction of these lines are unknown, because
in some regions of the body there are differences between different
individuals

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Correct Answer - A
Ans. is 'a' i.e., N. gonococci
Information in this question are ?
1. Gram negative diplococci.
2. Growth on modified Thayer-martin media.
o Neisseria gonorrhoeae is a gram negative diplococci and Thayermartin medium is the selective medium for gonococci.
Lab diagnosis of gonorrhea
Urethral discharge is the most important specimen.
Transport media
1. La It processing is to occur within 6 hrs ---> Stuart medium or A mies medium.
2. If processing is to occur > 6 hrs —> JEMBEC or Gono - Pak
system (media with self - contained CO2 -generating system).

Cluture media
1. In acute cases --> Chocolate agar or Muller - Hinton agar.
2. In chronic cases ---> Selective medium - Thayer martin medium.
Normally the diagnosis of gonorrhoea is made by isolating the organism in culture

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Dermatology

Correct Answer - D
Ans. D. DNA repair defect
[Ref Rook's 4thie p. 78.12]

Xeroderma pigmentosa
Molecular defect:
Exposure to UV rays damages DNA due to production of convalent
linkages between adjacent pyrimidines (pyrimidine dimmers).

Normally the damaged DNA is repaired by excision and repair.

In xeroderma pigmentosa the repair of UV damaged DNA is defective.
It is an autosomal recessive disorder

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[9.2] A 59-year-old man is admitted to the intensive care unit for a myocar- dial infarction. He is given a ẞ-adrenergic antagonist and instructed to avoid emotional turmoil to decrease sympathetic stimulation of the heart. From a cellular perspective, sympathetic stimulation of the heart does which of the following?

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Dermatology

A previously healthy, 27-year-old agricultural worker develops nausea, vomiting, abdominal cramps, cough with wheezing and dyspnoea, salivation, and lacrimation 1 hour after leaving work in a field. On examination, he is afebrile with a heart rate of 50/min and blood pressure of 90/55 mm Hg. Laboratory studies show plasma cholinesterase activity less than 50% of normal. Atropine is given intravenously, and his condition improves. He was most likely exposed to which of the following substances?

A Aflatoxin
B Cyclodiene
C Dioxin
D Ergot alkaloid
E Organophosphate

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A 30-year-old woman presents with complaints of fatigue, dizziness, and shortness of breath on exertion for the past few weeks. On physical examination, a systolic murmur is noted at the left sternal border, with no signs of heart failure or valvular abnormalities. Laboratory findings reveal a hemoglobin of 7.5 g/dL, MCV of 72 fL, and low ferritin levels. Her reticulocyte count is slightly elevated. Which of the following is the most likely cause of the murmur in this patient?

A) Iron-deficiency anemia
B) Thalassemia minor
C) Aortic regurgitation
D) Mitral valve prolapse
E) Sickle cell disease

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Dermatology

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Dermatology

Correct Answer - D
Ans. D. Lichen planus

LP is characterized by shiny, violaceous, flat-topped polygonal
papules which retain the skin lines.

White lines, known as Wickham's striae, may traverse the surface of
the papules.

Linear lesions often appear along scratch marks or in scars
(Koebner phenomenon).

In most cases, the papules eventually flatten after a 6 months to 2 yrs, often to be replaced by an area of hyperpigmentation.

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Dermatology

Correct Answer - B
Ans. B. Reverse Koebner's phenomenon


Annular orange skin lesions in a diabetic indicate towards granuloma annulare.

There have been few reports of disappearance of lesions after
biopsy in granuloma annulare.
This phenomenon is known as reverse Koebner's phenomenon.

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Dermatology

Correct Answer - D
Ans. D. DNA repair defect
[Ref Rook's 4thie p. 78.12]

Xeroderma pigmentosa
Molecular defect:

Exposure to UV rays damages DNA due to production of convalent
linkages between adjacent pyrimidines (pyrimidine dimmers).

Normally the damaged DNA is repaired by excision and repair.

In xeroderma pigmentosa the repair of UV damaged DNA is
defective.

It is an autosomal recessive disorder.

@dermatology_vid

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Dermatology

Correct Answer - B
Ans. is 'b' i.e., Bechet's syndrome
Criteria for diagnosis of Bechet's disease

Recurrent oral ulcer for at least 3 times in 12 months.
Plus any two of the followings :?
1. Recurrent genital ulcer.
2. Eye inflammation with loss of vision.
3. Characterstic skin lesion (erythema nodosum).
4. Positive pathergy test (skin prick test)

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Dermatology

Correct Answer - A
Answer- A. Palpable purpura
Palpable purpura is essential for diagnosis.

Diagnosis is confirmed by presence of palpable purpura with normal
platelet count along with one or more of the following : abdominal
pain, arthralgia/arthritisand mesangial deposition of IgA.

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Dermatology

Correct Answer - A
Ans. A. Idiopathic
[Ref: Neena Khanna Yale p. 61, 63]

Erythema multiforme
Most of the cases of erythema multiforme are idiopathic, but
amongst the causative agents Herpes simplex virus is the most
important cause.


Erythema multiforme is an acute, often self limited erutption
characterized by a distinctive clinical eruption, the hallmark of which is the Target lesion (Iris lesion or Bulle's eye lesion).

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Dermatology

Correct Answer - C
Pemphigus vulgaris is an intraepidermal blistering disease.

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