Internal Medicine
28 May 2025 16:45
فیلم/لیورگل در درمان کبد چرب موثر نیست
🔹فانا: علیرضا استقامتی استاد غدد درون‌ریز و متابولیسم (بالغین) دانشگاه علوم پزشکی تهران در گفت‌وگو با فانا توضیح داد: بیماری کبد چرب هم در جامعه و هم در افراد دیابتی شایع است. حدود نیمی از افراد جامعه ممکن است کبد چرب داشته باشند. همچنین تا حدود دو سوم از افراد مبتلا به دیابت ممکن است دچار کبد چرب شوند. بیماری کبد چرب فقط تجمع چربی در کبد نیست. این بیماری باعث التهاب در کبد می‌شود و اگر کنترل نشود منجر به فیبروز، نارسایی کبدی یا سیروز و بدخیمی می‌شود. افراد مبتلا به کبد چرب مستعد ابتلا به بیماری‌های قلبی عروقی مانند سکته‌های قلبی و مغزی، نارسایی قلبی و ... هستند. تنها درمان فعلی کبد چرب، رژیم غذایی سالم و ورزش منظم است. داروهای جدید درمان چاقی ممکن است روی التهابات کبد و فیروز هم اثر بگذارند و اگر مطالعات آنها کامل شود شاید در آینده بتوانیم از آنها هم استفاده کنیم. عرقیات و لیورگل هیچیک از نظر علمی، شواهد مستند و علمی برای درمان کبد چرب ندارند. قهوه هم در مطالعات مشاهده‌ای تا حدی در درمان کبد چرب موثر بوده است
@
Читать полностью…
Internal Medicine
18 May 2025 23:12
💢 The ’Silk Road’ that Leads to Infliximab: A Severe Case of Behcet’s Disease
🆔 @
.
Читать полностью…
Internal Medicine
12 May 2025 22:07
💢 Lifestyle Modifications in MASLD Management
🆔 @
.
Читать полностью…
Internal Medicine
11 May 2025 14:35
💢 Adrenal insufficiency: identification and management—summary of new NICE guidance
🆔 @
.
Читать полностью…
Internal Medicine
06 May 2025 22:16
💢 Taking A Clinical History in Iron Deficiency Anemia
🆔 @
.
Читать полностью…
Internal Medicine
05 May 2025 09:08
💢 Pigmented Lesion on the Hard Palate
🆔 @
.
Читать полностью…
Internal Medicine
30 Apr 2025 23:19
💢 Gout 2025
🆔 @
.
Читать полностью…
Internal Medicine
29 Apr 2025 21:05
سلام
اطلاعاتی در مورد بیماری سرخک برای کادر سلامت.
امیدوارم که مورد استفاده قرار گیرد.
خوش حال می‌شوم که پاسخ گوی پرسش ها باشم.🙏🏻
Читать полностью…
Internal Medicine
19 Apr 2025 16:43
💢 CT Scans Linked to New Cancer Diagnoses in U.S., But Overall Risk is Low
A recent study highlighted in JAMA Internal Medicine suggests that computed tomography (CT) scans may slightly increase a person's lifetime risk of developing cancer due to exposure to ionizing radiation.
The cumulative effect of repeated scans over time is of particular concern, especially as the number of CT scans performed in the United States has risen by over 30% since 2007.
The study estimates that CT scans performed in 2023 could be linked to approximately 103,000 future cancer cases, potentially accounting for about 5% of all new cancer diagnoses in the United States.
The risk is higher in children and adolescents compared to adults, with the most common projected cancers in adults being lung, colon, leukemia, and bladder cancer. In women, breast cancer was the second most common, while in children, thyroid, lung, and breast cancers were most frequently projected.
The highest number of cancers in adults was projected to result from CT scans of the abdomen and pelvis, followed by chest scans. In children, head CT scans were most associated with future cancer risk.
Despite these projections, experts emphasize that the absolute risk remains minimal and must be considered over decades of follow-up.
Balancing Benefits and Risks
CT scans are crucial diagnostic tools, often saving lives by enabling early detection and treatment of serious conditions such as cancer, blood clots, and internal bleeding.
The American College of Radiology (ACR) and other experts stress that, while the theoretical cancer risk exists, the benefits of medically necessary CT scans far outweigh the risks, especially when used appropriately.
CT imaging has been directly linked to declining cancer death rates, reduced need for invasive surgeries, and improved life expectancy.
Experts recommend that patients and healthcare providers engage in shared decision-making, weighing the necessity and frequency of CT scans against potential risks.
Reducing the number of unnecessary scans and lowering the dose per scan are practical steps to decrease potential future cancer cases.
🆔 @
.
Читать полностью…
Internal Medicine
18 Apr 2025 16:22
💢 Cannabis and Cannabinoids for Chronic Non-cancer Pain: Guidance from the ACP
Cannabis-based products can be prescribed legally for medicinal uses in some U.S. states, and many patients (regardless of their local laws) use these products to manage chronic pain.
The ACP now has published best-practice advice on risks and benefits of cannabis and cannabinoids for chronic non-cancer pain; the authors' analysis was based primarily on 26 randomized trials and 12 observational studies, most of which focused on neuropathic pain.
Products with high ratios of Δ-9-tetrahydrocannabinol (THC) to cannabidiol (CBD) — i.e., ≥2:1 — were associated with small improvements in pain and medium-to-high risks for dizziness, nausea, and sedation compared with placebo or usual care.
Products with low THC–CBD ratios (<1:2) did not improve pain and were associated with medium-to-high risks for dizziness, nausea, and sedation.
Potential long-term harms included cannabis use disorder, cognition changes, cannabis hyperemesis syndrome, and psychosis.
Clinicians should counsel patients about potential benefits and harms of using cannabis and cannabinoids for chronic non-cancer pain. The authors give three additional recommendations:
- Harms likely outweigh benefits for young adults (age, ≤25), patients with substance use disorder (past or current) or serious mental illness, and those with high risk for falls.
- Patients who are pregnant, breastfeeding, or actively trying to conceive should not use these products.
- All patients should avoid inhaled cannabis.
COMMENT
The information in this advisory will help guide conversations with patients. It is most applicable to clinicians and patients in states with “medical” cannabis-based products and robust quality-control measures. Outside of these regulatory frameworks, the content of cannabis-based products can differ substantially from product labeling, given limited oversight of production
🆔 @
.
Читать полностью…
Internal Medicine
16 Apr 2025 22:38
🆔 @
.
Читать полностью…
Internal Medicine
06 Apr 2025 18:03
💢 The Evolving Role of Weight Loss
Pharmacotherapy
🆔 @
.
Читать полностью…
4554